Kreylos, O, Billen, M I, Kellogg, L H, Hamann, B, Sumner, D Y, Staadt, O and Jadamec, M (2006), Environment-independent 3D Visualization Software for Geo-science Applications, Eos Trans. AGU, 87(52), Fall Meet. Suppl., Abstract IN31A-1310 It has long been known that graphical representations of data in 2D provides efficient and insightful ways of interpreting quantitative information, but similar analysis of higher dimensional data sets has lagged behind 2D graphics. Many scientists view 3D visualizations as something one makes once the data has already been understood, rather than a tool for exploring and analyzing data in which the features of interest are yet to be discovered. One reason for this view may be that the design of 3D volume visualization software has focused on providing an environment for users to create a final image, rather than providing the interactive environment and real-time rendering required to visually analyze large 3D volume data sets. We present a user study of 3D volume visualization software, Visualizer, which has been specifically designed to create a flexible, intuitive environment for interactive, scientific analysis of 3D volume data sets. Visualizer runs in a range of 3D VR environments (e.g., GeoWall, ImmersaDesk, CAVE), but also provides a similar level of real-time interactivity on a desktop computer. To assess how specific tools aid researchers in navigating through and identifying features in 3D data using a 2D viewing environment, in the first part of the study we compared Visualizer on a desktop computer to a commercial visualization package, TecPlot (http://www.tecplot.com). In the second part of the study, Visualizer was also used in a 4-sided immersive visualization CAVE environment. Geoscientists ranging from undergraduates to university faculty were asked to identify features in a 3D model of a subducting slab. Visualizer used in the CAVE proved easiest to use overall and made data exploration (navigating, identifying and locating features) the easiest. Visualizer used on the desktop also made data exploration easier than TecPlot, but users found it more difficult to learn. Comments from participants provided insightful feedback on how to improve Visualizer for the desktop and supports the conclusion that Visualizer is intuitive, easy-to-use and allows geoscientists to efficiently and effectively analyze 3D volume data sets.